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XDR TB
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http://www.mja.com.au/journal/2013/198/7/extensively-drug-resistant-tuberculosis-hovers-threateningly-australia-s-door
XDR-TB raises concerns of a future TB epidemic with restricted treatment options, and jeopardizes the major gains made in TB control.
http://en.wikipedia.org/wiki/Extensively_drug-resistant_tuberculosis
This is surely of very significant concern. Perhaps it will be the first really significant antibiotic-resistant disease to ravage humanity… with many more to follow.
It would appear that it IS going to come to Australia, and IS going to spread rapidly abroad. It is already known from various other parts of the world.
And it would appear that newly evolving strains of all manner of diseases will appear and wreak havoc on humanity.
Now for the really controversial bit – Perhaps in the long term this could actually be a good thing, if it brings the human population down by a couple of billion.